Adrenal gland transplantation in clinical conditions

Chronic insufficiency of the cortical substance adrenal glands or hypocorticism until recently belonged to rare forms endocrine pathology. This included a few cases Addison’s disease tuberculous etiology, relatively small number patients after bilateral adrenalectomy for Cushing’s disease, removal bilateral, sometimes unilateral, hormonally active tumors cortex and medulla glands. Bilateral is also practiced some types hormone‑dependent mammary glands, ovaries, prostate, malignant hypertension. The evolution ideas about pathophysiology contributed significant expansion increase in suffering from hypocorticism. A decrease incidence tuberculosis with classic disease. However, an increasing autoimmune, genetically determined other genesis are currently being discovered. improvement diagnostic methods contributes operations and, accordingly, post‑adrenalectomy Operations on pituitary gland various tumors, which steadily increasing, contribute hypothyroidism. In mid‑70s XX century. new direction treatment by method transplanting cultures cells tissues took shape. Disorders seem be particularly suitable transplantation treatment, since it expected that living functionally donor tissue, transplanted into patient insufficiency, will secrete hormones provide body’s physiological needs clinical compensation insufficiency. Similar experimental studies have been conducted beginning 20th obtaining organs were developed detail, issue their viability, morphological hormonal characteristics, possibility certain studied.